It's not about things like time of year, or playing someone early/late being better. It depends on things like injuries/availability of players, new players having settled or not, general team form etc. One example is things like our rivals' games against top teams and the timing of them - if we're engaged in a battle for 4th with Man Utd, them having (for example) Arsenal, City & Chelsea in late April & into May, is largely rubbish for us because most things are usually settled by then. Likewise, you're better off not facing sides who'll be in a relegation battle towards the last few or eight games because those who do perform the great escape, often produce results during this period. There's all kinds of variables but without knowing things like injuries and form, it's impossible to make a statement as to when it's best to play certain sides.